CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 COMPLEXED WITH 3R-HYDROXY-4E-DECENOYL-CoA AND REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE

CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 COMPLEXED WITH 3R-HYDROXY-4E-DECENOYL-CoA AND REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE Descriptor: (S)-3-HYDROXY-(E)-4-DECENOYL-COA, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Peroxisomal bifunctional enzyme, ... Authors: Kiema, T.-R, Wierenga, R.K, Sirdhar, S. Deposit date: 2026-02-05 Release date: 2026-07-22 Last modified: 2026-07-29 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Structural enzymological studies of multifunctional enzyme, type-1 (MFE1) with the 2E-decenoyl-CoA and 2E,4E-decadienoyl-CoA substrates: The regeneration of the dehydrogenase catalytic site is the rate limiting step of its combined reactions. J.Struct.Biol., 218, 2026