Additional file 8 of Targeting activated PI3K/mTOR signaling overcomes acquired resistance to CDK4/6-based therapies in preclinical models of hormone receptor-positive breast cancer

Additional file 8: Table S5. Pharmacodynamic changes in protein levels in treated groups relative to vehicle control. As measured by RPPA. Normalized, median-centered log (expression) values were calculated for each sample, mean expression values were calculated for replicate mice within each treatment group. Alterations in protein expression between each treatment group and the vehicle control were calculated as the mean fold change in expression compared to control (parental baseline – or untreated/vehicle treated control samples).