Values given as percentage or mean±SD. BMI = body mass index; BNP = B-type natriuretic peptide; CK = creatine kinase; CK-MB = creatine kinase-MB fraction; CRP = C-reactive protein.
We performed single cell RNA sequencing (scRNA-seq) for 6,574 cells from the aortic valves of C57BL/6J (wild type), Ldlr-/-, and Apoe-/- mice. The extensive single cell profiles depicted hyperlipidemi