The mammalian heart undergoes maturation during postnatal life to meet the increased functional requirements of the adult. However, the key drivers of this process remain poorly defined. We developed
Rats (8 weeks old) were fed the control diet or the Mg-deficient diet for 4–6 weeks, and [Mg2+]i was measured with the fluorescent indicator furaptra in the myocytes isolated from control rats (Contro
Statins prevent cardiovascular disease via their salutary function as inhibitors of cholesterol biosynthesis and mediators of pleiotropic effects on the cardiovascular system. The current study focuse
Obesity and high saturated fat intake increase the risk of heart failure and arrhythmias. The molecular mechanisms are poorly understood. We hypothesized that physiologic levels of saturated fat could