A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.

ChEBI2015-01-30 更新2026-07-21 收录

巨噬细胞调控

转录因子功能研究

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A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.

创建时间：

2015-01-30

Human Amniotic Epithelial Cell Transplantation Induces Markers of Alternative Macrophage Activation and Reduces Established Hepatic Fibrosis

肝纤维化细胞治疗

巨噬细胞调控

Chronic hepatic inflammation from multiple etiologies leads to a fibrogenic response that can progress to cirrhosis and liver failure. Transplantation of human amniotic epithelial cells (hAEC) from te

NIAID Data Ecosystem60

Gene expression analysis of mouse pancreas carrying Prox1 ectopic acinar expression

胰腺基因表达

转录因子功能研究

RNA sequencing was used to identify gene expression changes in pancreatic acinar cells with ectopic expression of the homeodomain transcription factor Prox1 Overall design: The pancreas P7 control mic

NIAID Data Ecosystem40

Investigate the effect of gain of HAND2 on chromatin accessibility.

染色质可及性分析

转录因子功能研究

The overexpression of HAND2 in IMR32 cells results in a increase of chromation accessibility at the HAND2 and MYCN common binding sites. Overall design: In the HAND2 stably transfected IMR32 cells (IM

NIAID Data Ecosystem20

Foxf2 plays a dual role during TGFb-induced EMT by promoting apoptosis yet enabling cell junction dissolution and migration.. Foxf2 plays a dual role during TGFb-induced EMT by promoting apoptosis yet enabling cell junction dissolution and migration.

上皮-间质转化机制

转录因子功能研究

We have identified the transcription factor forkhead box protein F2 (Foxf2) to be upregulated in its expression during the EMT process and studied its functional contribution to EMT by siRNA-mediated

NIAID Data Ecosystem50

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ATACseq]

先天性贫血分子机制

转录因子功能研究

Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, al

NIAID Data Ecosystem40

A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.

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