SIRT7 is a histone H3 lysine 18 deacetylase that regulates oncogenic transformation

ChEBI2012-05-06 更新2026-07-21 收录

组蛋白修饰酶功能

癌症表观遗传学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-28149 数据链接链接失效反馈

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SIRT7 is a histone H3 lysine 18 deacetylase that regulates oncogenic transformation

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2012-05-06

Global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines investigated by UPLC-MS/MS

癌症表观遗传学

甲基化测序

We performed UPLC-MS/MS to investigate global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines (97L and LM6 cells). We found that 5mC and 5hmC were frequently dec

Figshare2016-01-19 更新70

Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients

癌症表观遗传学

药物耐药性

Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic

DataONE2020-06-24 更新60

Summary of OPCML methylation in cell lines and primary tumors.

癌症表观遗传学

DNA甲基化分析

Summary of OPCML methylation in cell lines and primary tumors.

NIAID Data Ecosystem30

Additional file 4 of Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines

癌症表观遗传学

肿瘤化疗敏感性预测

Additional file 4: Table S4. Significant strong trans- and cis-correlations of GMD expression with methylation of individual probes in the pancancer dataset satisfying p 0.5.

Figshare2021-03-06 更新60

Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch [methylation]

癌症表观遗传学

癌细胞异质性

Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests t

NIAID Data Ecosystem40

SIRT7 is a histone H3 lysine 18 deacetylase that regulates oncogenic transformation

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