Development of gene expression signatures for ANP in HUVEC. Homo sapiens

Analysis of HUVEC treated with ANP. ANP is a cardiac hormone, binding to the guanylate cyclase-A (GC-A) receptor with a major role in cardiovascular homeostatic mechanisms. Results provide insight into the molecular mechanisms of ANP in vascular endothelial cell. Overall design: ANP induced gene expression in HUVEC was measured at 0, 1 and 6 hours. Four independent experiments were performed at each time (0, 1 or 6 hours) for each experiment.