Cecal microbiome of C-, WD- and REV-dams at weaning and in their offspring (C-offspring, WD-offspring, and REV-offspring, respectively) at 4 months.. Maternal and offspring

We aimed to analyze the effects of maternal obesity and/or obesogenic diet consumption on gut microbiome of mothers and their offspring in adulthood, together with the effects of leptin supplementation during suckling. Three groups of rats were studied: Control dams, Western diet dams, and Reversion dams. Their offspring were supplemented throughout suckling with leptin/vehicle and weaned on a Standard diet.