Co-crystal structure of HIV-1 protease bound to a mutant resistant inhibitor UIC-98038
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Co-crystal structure of HIV-1 protease bound to a mutant resistant inhibitor UIC-98038 Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL [(1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL]CARBAMATE, HIV-1 protease Authors: Hong, L, Tang, J, Ghosh, A. Deposit date: 2009-07-08 Release date: 2009-09-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Design, Synthesis, Protein-Ligand X-ray Structure, and Biological Evaluation of a Series of Novel Macrocyclic Human Immunodeficiency Virus-1 Protease Inhibitors to Combat Drug Resistance. J.Med.Chem., 52, 2009
创建时间:
2009-07-08



