Applications of artificial intelligence to lipid nanoparticle delivery
收藏科学数据银行2024-10-10 更新2026-04-23 收录
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资源简介：
Lipid nanoparticles (LNPs) are nanocarriers composed of four lipid components and can be used for gene therapy, protein replacement, and vaccine development. However, LNPs also face several challenges, such as toxicity, immune activation, and low delivery efficiency. To overcome these challenges, artificial intelligence can be used to optimize the design and formulation of LNPs, as well as to predict their properties and performance. Moreover, antibody-targeted conjugation can be used to enhance the specificity and selectivity of LNPs by attaching an antibody that recognizes a specific antigen on the cell surface to LNPs.
提供机构：
Yuqi Wu; Jiabei Cheng; Hongguang Wu; Xiaoyong Pan; Shanghai Jiao Tong University; Kaiyuan Yang; Yilin Xia
创建时间：
2024-10-10
