VIP (variable importance in projection) metabolites.

Mean liver (2A) and muscle (2B) values are reported as mM/1 g lyophilyzed muscle tissue. Mean serum (2C) values are reported as mmol/L. The lab values of urea (obtained with a Gem Premier 3000 blood gas analyzer) are reported instead of NMR values since the water suppression in the CPMG pulse sequence compromises the urea signal. Mean urine (2D) values are reported as nmol/hr/kg. Bolded numbers indicate metabolites that achieved VIP scores above 1.0 or were the top 10 metabolites of those metabolites with VIP scores above 1.0. Only the Baseline serum urea (laboratory analysis) reached statistical significance (p = 0.003, Student T test assuming unequal variance).VIP (variable importance in projection) metabolites.