Crystal structure of ERK2 in complex with an inhibitor 14K

Crystal structure of ERK2 in complex with an inhibitor 14K Descriptor: 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(tetrahydro-2H-pyran-4-ylamino)pyrimidin-4-yl]pyridin-2(1H)-one, Mitogen-activated protein kinase 1 Authors: Yin, J, Wang, W. Deposit date: 2015-01-08 Release date: 2015-09-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Discovery of highly potent, selective, and efficacious small molecule inhibitors of ERK1/2. J.Med.Chem., 58, 2015