RNA-Seq analysis of primary AML specimens exposed to AhR modulating agents
收藏官方服务：
资源简介：
RNA-Seq analysis of primary AML specimens exposed to AhR modulating agents
应用场景：
创建时间：
2016-07-20
相关数据集
Additional file 3 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax
Additional file 3: Supplementary Table 3.
DataCite Commons2024-02-13 更新100
Discovery of Dual CDK6/PIM1 Inhibitors with a Novel Structure, High Potency, and Favorable Druggability for the Treatment of Acute Myeloid Leukemia
Nowadays, the simultaneous inhibition of two or more pathways plays an increasingly important role in cancer treatment due to the complex and diverse pathogenesis of cancer, and the combination of the
NIAID Data Ecosystem50
Discovery of a Potent FLT3 Inhibitor (LT-850-166) with the Capacity of Overcoming a Variety of FLT3 Mutations
Secondary mutations of FLT3 have become the main mechanism of FLT3 inhibitor resistance that presents a significant clinical challenge. Herein, a series of pyrazole-3-amine derivatives were synthesize
NIAID Data Ecosystem20
Toosendanin Suppresses Acute Myeloid Leukemia by Targeting DDX5/c-Myc Axis to inhibit Protein Synthesis
The treatment of acute myeloid leukemia (AML) continues to be challenged by relapse and resistance, necessitating the development of novel therapeutic strategies. Toosendanin (TSN), a natural product
NIAID Data Ecosystem70
RNA-seq of MV-4-11 or THP-1 cells treated with LSD1 inhibitor INCB059872. RNA-seq of MV-4-11 or THP-1 cells treated with LSD1 inhibitor INCB059872
INCB059872 is a selective irreversible inhibitor of Lysine-Specific Demethylase 1 (LSD1) that is in phase 1 clinical trials in hematopoietic malignancies. LSD1 inhibition can induce differentiation of
NIAID Data Ecosystem30
