Gut microbiome of mice with diet-induced obesity. Gut Microbiome of Mice with Diet-Induced Obesity

Total community DNA was isolated from the cecal contents of seven wild-type C57BL/6J mice fed different types of diets. Mice with obesity produced by consumption of a high-fat/high-sugar Western diet develop a bloom of an uncultured distal gut bacterial lineage. Comparative metagenomic studies of this community provides information about this organism's niche, and emphasize how diet and the gut bacterial community are interrelated variables in the energy balance equation.