Lewis Lung Carcinoma (LLC) cells in the lung model express lung-specific genes compared to subcutaneous engraftment cells.
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE208373
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We revealed that tumor cells in the bleomycin-injured lungs (BLM lungs) are differently influenced by their unique lung fibrogenic microenvironment compared to those in subcutaneous tumor models in vivo or in 2-dimensional monolayer culture in vitro. The gene expression profiles of LLC cells grown in 2-dimensional monolayer culture, in subcutaneous tumors, and in BLM lungs were analyzed (n=3/group).
创建时间:
2022-09-15



