Alterations of DNA Methylation Profile in Peripheral Blood of Children with Simple Obesity

Genome wide DNA methylation profiling of peripheral blood samples from 41 children with simple obesity and 31 normal controls. The Illumina Infinium MethylationEPIC BeadChip (Illumina 850k, San Diego, CA) was used to obtain DNA methylation profiles across greater than 850,000 CpG sites across the genome. Samples included 31 normal and 41 obesity peripheral blood. Bisulphite converted DNA from the 72 samples were hybridised to the Illumina Infinium MethylationEPIC BeadChip (Illumina 850k, San Diego, CA).