Mouse Embryo Sox1 cre-dependent knockout of EED

NIAID Data Ecosystem2026-05-26 收录

发育表观遗传调控

条件性基因敲除

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP133646 数据链接链接失效反馈

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资源简介：

Floxed EED homozygote mice are knocked-out by Sox1-driven Cre to remove H3K27me3 during neurogenesis Overall design: Control mice are compared to EED-cKO mice in bulk RNAseq, in dissected forebrain and spinal cord

创建时间：

2019-02-23

DNA Methyaltion of Human Cortical Organoids

发育表观遗传调控

器官DNA甲基化

Assesing DNA methylation patterns of human cortical organoids during long term (>600 days) maturation. 52 samples collected during long term maturation of human cortical spheroids

NIAID Data Ecosystem90

Expression profiling of LSK cells from Bmi1 cKO mice in hematopoiesis versus LSK control cells from WT mice

造血干细胞基因表达

条件性基因敲除

Expression profiling of LSK cells from Bmi1 cKO mice in hematopoiesis versus LSK control cells from WT mice

ChEBI2011-10-29 更新10

Single cell approaches define two mammalian oligodendrocyte precursor cell populations and their evolution over developmental time [scATAC-seq]. Single cell approaches define two mammalian oligodendrocyte precursor cell populations and their evolution over developmental time [scATAC-seq]

少突胶质前体细胞

发育表观遗传调控

Here, we have used single-cell RNA sequencing (scRNA-seq), single-cell ATAC sequencing (scATAC-seq) and spatial transcriptomics to characterize murine cortical OPCs throughout postnatal life. During d

NIAID Data Ecosystem00

Genome-wide maps of chromatin state in 5-HT6R knock out mice.. Genome-wide maps of chromatin state in 5-HT6R knock out mice.

发育表观遗传调控

神经元兴奋性调控

Purpose:The primary cilia play central roles in transducing or regulating various signaling pathways during brain development. However, the function of primary cilia in mature nerve system is currentl

NIAID Data Ecosystem60

Catalytic-dependent and independent functions of the histone acetyltransferase CBP promote pioneer factor-mediated zygotic genome activation [PRO-Seq]

发育表观遗传调控

合子基因组激活转录机制

Immediately after fertilization the genome is transcriptionally quiescent. Maternally encoded pioneer transcription factors reprogram the chromatin state and facilitate the transcription of the zygoti

NIAID Data Ecosystem10

Mouse Embryo Sox1 cre-dependent knockout of EED

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