Genome-wide analysis of gene expression in response to bortezomib treatment

ChEBI2013-07-02 更新2026-07-21 收录

药物基因组学

癌症治疗响应

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-41930 数据链接链接失效反馈

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Genome-wide analysis of gene expression in response to bortezomib treatment

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2013-07-02

CYP2C19 genotype of 30 Chinese critically ill patients

药物基因组学

危重患者个体化用药

CYP2C19 is one of the most important drug metabolizing enzymes in human body. The gene base is located in chromosome region 10q 24.2 and consists of 9 exons. CYP2C19 has many single nucleotide polymor

Figshare2021-11-16 更新70

Pharmacogenomic comparison between D3T- and CDDO-Im in mouse liver tissue. Mus musculus

药物基因组学

化学预防

The Keap1/Nrf2 signaling pathway is a tractable target for the pharmacological prevention of tumorigenesis. 3H-1,2-dithiole-3-thione (D3T) and 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole

NIAID Data Ecosystem60

Impact of CYP3A5 Genotypes on Tacrolimus Pharmacokinetics in Colombian Liver Transplant Patients

肝移植免疫抑制

药物基因组学

Impact of CYP3A5 Genotypes on Tacrolimus Pharmacokinetics in Colombian Liver Transplant Patients

Zenodo2024-10-22 更新30

Additional file 2: of Connecting genetics and gene expression data for target prioritisation and drug repositioning

药物基因组学

基因表达分析

Table S2. List of current drug indications with a significant overlap between genes significantly up- or down-regulated after drug treatment and GWAS hits. Results are filtered for adjusted p-value

DataCite Commons2020-08-29 更新70

Table2_Genetic Epidemiology of Medication Safety and Efficacy Related Variants in the Central Han Chinese Population With Whole Genome Sequencing.xlsx

药物基因组学

遗传流行病学

Medication safety and efficacy-related pharmacogenomic research play a critical role in precision medicine. This study comprehensively analyzed the pharmacogenomic profiles of the central Han Chinese

NIAID Data Ecosystem50

Genome-wide analysis of gene expression in response to bortezomib treatment

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