Induction of human SST and PV neurons by expressing a single transcription factor LHX6. Induction of human SST and PV neurons by expressing a single transcription factor LHX6

To systematically explore the effect of LHX6 on neural development and differentiation, we performed RNA-sequencing (RNA-seq) of hPSC-derived GINs at day 50 in vitro.RNAseq results could also confirm alteration of GINs identity with the overexpression of LHX6. Overall design: RNAs-seq assay of two groups of GABAergic neurons (control and LHX6 overexpression)