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Smiles Rearrangement as a Tool for the Preparation of Dihydrodipyridopyrazines

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NIAID Data Ecosystem2026-03-06 收录
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A novel methodology for the synthesis of isomer A of dihydrodipyridopyrazines was developed. The key transformation features a Smiles rearrangement of nitro substituted N,N′-dipyridinylamines, potential precursors of isomer B obtained by the alkylation of compounds prepared by a Pd-catalyzed reaction and subsequent cyclization.

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2016-02-25
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