Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation.

NIAID Data Ecosystem2026-05-02 收录

转录终止机制

piRNA表观遗传调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE291110 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2025-03-06

Terminator RNAseq (TermSeq) of a synthetic library of intrinsic terminators.

转录终止机制

高通量RNA测序验证

Proof-of-concept validation of a custom intrinsic terminator synthesis and high-throughput terminator RNAseq (TermSeq) methodologies to identify library terminators and quantify their termination effi

NIAID Data Ecosystem80

Transcription of mammalian cis-regulatory elements is restrained by actively enforced early termination [RNA]. Mus musculus

转录终止机制

非编码RNA调控

Upon recruitment to active enhancers and promoters, RNA polymerase II (Pol_II) generates short non-coding transcripts of unclear function. The mechanisms that control the length and the amount of ncRN

NIAID Data Ecosystem80

Crystal Structure of the MTERF1 F322A substitution bound to the termination sequence.

DNA相互作用

转录终止机制

Crystal Structure of the MTERF1 F322A substitution bound to the termination sequence. Descriptor: DNA (5'-D(*AP*TP*TP*AP*CP*CP*GP*GP*GP*CP*TP*CP*TP*GP*CP*CP*AP*TP*CP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*

Protein Data Bank Japan2023-09-27 更新40

Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex.

转录终止机制

细菌蛋白复合物结构

Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex. Descriptor: 30S ribosomal protein S10, N utilization substance protein B Authors: Luo, X, Wahl, M.C. D

Protein Data Bank Japan2023-08-30 更新80

RNA-seq of total RNA in budding yeast wild-type and rrp6∆ strains, and in dbr1∆ or sen1-1 dbr1∆ strains expressing either a control or decoy RNA.. RNA-seq of total RNA in budding yeast wild-type and rrp6∆ strains, and in dbr1∆ or sen1-1 dbr1∆ strains expressing either a control or decoy RNA.

转录终止机制

RNA代谢

We obtained transcriptome profiles of different S.cerevisiae strains. This allowed us to determine the impact of defective nuclear exosome and expression of an RNA decoy on NNS-dependent transcription

NIAID Data Ecosystem40

Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation.

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