Stability assessment of KY-NAb-GDF15 antibody using SEC-HPLC and ELISA techniques following various treatments.

The stability testing of KY-NAb-GDF15 was performed under different acceleration conditions, including 5 freeze-thaw cycles, low pH treatment, high-temperature treatment for 1 week and 2 weeks, as well as stability analysis in plasma. Before and after treatment, KY-NAb-GDF15 was analyzed using SEC-HPLC and ELISA to detect changes in integrity and binding function.