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MHC Ligandomes of Reovirus-Treated Tumors

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NIAID Data Ecosystem2026-03-11 收录
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Using a mass spectrometry (MS)-based MHC-I ligandome discovery platform, we determined differential tumor MHC-I ligand expression following treatment with oncolytic reovirus in a murine ovarian cancer model. We then tested the immunogenicity and antitumor immune effects of CD8 T cells specific to these reovirus-induced ligands.

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2019-04-23
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