Factor XA in complex with a cis-1,2-diaminocyclohexane derivative
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Factor XA in complex with a cis-1,2-diaminocyclohexane derivative Descriptor: 7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide, Activated factor Xa heavy chain, CALCIUM ION, ... Authors: Suzuki, M. Deposit date: 2009-08-03 Release date: 2010-08-04 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties. Bioorg.Med.Chem., 17, 2009
创建时间：
2009-08-03
