首页/数据集/Metformin promotes female germline stem cell proliferation by upregulating Gata-binding protein 2 with histone β-hydroxybutyrylation.

Metformin promotes female germline stem cell proliferation by upregulating Gata-binding protein 2 with histone β-hydroxybutyrylation.

NIAID Data Ecosystem2026-05-01 收录

生殖干细胞调控

表观遗传药物机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE217784 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-06-05

生殖干细胞调控

精子发生

Spermatogonial stem cells (SSCs) have the dual capacity to self-renew and differentiate into progenitor spermatogonia that develop into mature spermatozoa. Here, we document that preferentially expres

NIAID Data Ecosystem90

Increased H3K27 trimethylation contributes to cone survival in a mouse model of cone dystrophy. Increased H3K27 trimethylation contributes to cone survival in a mouse model of cone dystrophy

视网膜疾病治疗

表观遗传药物机制

Inherited retinal diseases (IRDs) are a heterogeneous group of blinding disorders, which result in dysfunction or death of the light-sensing cone and rod photoreceptors. Despite individual IRDs being

NIAID Data Ecosystem50

Additional file 7 of Epigenetic remodeling to improve the efficacy of immunotherapy in human glioblastoma: pre-clinical evidence for development of new immunotherapy approaches

胶质母细胞瘤免疫治疗

表观遗传药物机制

Additional file 7: Table S1: Upstream regulators by guadecitabine in all tumor types; Table S2: Enrichment analysis of Upstream regulators up-regulated in GBM vs MM-BM; Table S3: Enrichment analysis o

NIAID Data Ecosystem40

RIP-chip analysis of the C. elegans PUF protein FBF

RNA结合蛋白靶标

生殖干细胞调控

The PUF family of RNA binding proteins has a conserved role in maintaining stem cell self-renewal. FBF is a C. elegans PUF that is required to maintain germline stem cells (GSCs). To understand how

NIAID Data Ecosystem60

The phosphorylated prodrug FTY720 is a histone deacetylase Q15 inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer

癌症靶向治疗

表观遗传药物机制

Nuclear FTY720-P is a potent inhibitor of class I histone deacetylases (HDACs) that enhances histone acetylations and regulates expression of a restricted set of genes independently of its known effec

NIAID Data Ecosystem50

Metformin promotes female germline stem cell proliferation by upregulating Gata-binding protein 2 with histone β-hydroxybutyrylation.

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