The underlying cause of thrombosis in a large protein C (PC) deficient Vermont kindred appears to be multicausal and not explained by PC deficiency alone. We evaluated the contribution of coagulation
3D image reconstruction of a late stage thrombus is shown in (a) (luminal view) and (b) cross section in a vertical plane (wall is on the left, lumen is on the right). Regions composed mostly of plate
Glycoprotein VI–fragment crystallizable (GPVI-Fc) (50 μg/ml final concentration; 333 nM) labeled with phycoerythrin (PE)-conjugated anti–human-Fc antibody (red) was added to blood containing ab
Background and Objective Using an in vitro experimental model of immobilized tissue factor-initiated clot growth in platelet-free plasma (thrombodynamics), we observed formation of activator-independe