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资源简介：
Agxt off-target, Hao1 on/off-target
应用场景：
创建时间：
2020-06-06
相关数据集
A Type II-B Cas9 nuclease with no detectable off-targets and reduced chromosomal translocations in vivo.
Streptococcus pyogenes Cas9 (SpCas9) and derived enzymes are widely used as components of CRISPR-Cas9 genome editing and engineering platforms. However, they exhibit promiscuous nuclease activity that
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In vivo evaluation of guide-free Cas9 induced genomic damage and transcriptome changes using pig models (RNA-seq). Sus scrofa
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Comparing molecular and computational approaches for detecting viral integration of AAV gene therapy constructs
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Genome-wide off target detection of Un1Cas12f1 in mouse models
Hypercompact Cas12f1 were demonstrated with eukaryotic nuclease activity showing great potential as AAV-based gene therapy system. Our present study provided definitive results for developing Cas12f1-
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Integrome signatures of lentiviral gene therapy for SCID-X1 patients
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
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