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A Leptin Mediated Neural Mechanism Linking Breathing to Metabolism

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doi.org2025-01-21 收录
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http://doi.org/10.17632/z9ptfwbvd5.1
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This data set contains RNA sequencing results of leptin receptor expressing neurons in the Nucleus of the Solitary Tract. Single neurons were recorded with whole-cell patch clamp, then the cellular cytoplasm was harvested for RNA-sequencing. Two cell types were identified based on firing properties and were designated as "type1" and "type2" cells. Group1 (G1; Type1) samples: ID_1_1, ID_1_2, ID_4_3, ID_8_2, ID_9_1 Group2 (G2; Type2 GLP-1) samples: ID_6_2, ID_10_1, ID_10_3, ID_9_2, ID_9_4 Group3 (G3; Type2 Chat) samples: ID_6_4, ID_6_5 Excel files contain differential gene expressions: G1 vs G2, G1 vs G3, G2 vs G3

本数据集收录了位于孤束核中表达瘦素受体的神经元RNA测序结果。通过全细胞膜片钳技术对单个神经元进行记录,随后采集细胞质以进行RNA测序。根据放电特性识别出两种细胞类型,分别命名为“type1”和“type2”细胞。 组别1(G1;Type1)样本:ID_1_1, ID_1_2, ID_4_3, ID_8_2, ID_9_1 组别2(G2;Type2 GLP-1)样本:ID_6_2, ID_10_1, ID_10_3, ID_9_2, ID_9_4 组别3(G3;Type2 Chat)样本:ID_6_4, ID_6_5 Excel文件包含了差异基因表达分析结果:G1与G2、G1与G3、G2与G3。
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