H2A.Z.1 mono-ubiquitylation antagonizes BRD2 to maintain poised chromatin in ESCs

NIAID Data Ecosystem2026-03-08 收录

胚胎干细胞调控

组蛋白H2A.Z单泛素化

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA231111 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

创建时间：

2013-12-11

ChIP-Seq of Oct4 in Human Embryonic stem cells.. Homo sapiens

转录因子结合位点鉴定

胚胎干细胞调控

Oct4, Sox2 and Nanog cooperate to form the transcriptional regulatory circuitry of embyronic stem cells. To gain insight into the genes regulated by the core circuitry of transcription factors, chroma

NIAID Data Ecosystem100

A combined RNAi and localization approach for dissecting long noncoding RNAs reveals a function of Panct1 in ES cells. Mus musculus

lncRNA功能研究

胚胎干细胞调控

Long non-coding RNAs (lncRNAs) regulate diverse biological pathways. Unlike protein coding genes, where methods to comprehensibly study their functional roles in cellular systems are available, techni

NIAID Data Ecosystem60

H2A.Z.1 mono-ubiquitylation antagonizes BRD2 to maintain poised chromatin in ESCs

H2A.Z.1单泛素化

胚胎干细胞调控

Histone variant H2A.Z occupies the promoters of active and poised, bivalent genes in ESCs to regulate developmental programs, yet how it contributes to these contrasting states is poorly understood. H

NIAID Data Ecosystem40

A hyperdynamic H3.3 nucleosome marks promoter regions in pluripotent embryonic stem cells

表观遗传学

胚胎干细胞调控

Histone variants and their chaperones are key regulators of eukaryotic transcription, and are critical for normal development. The histone variant H3.3 has been shown to play important roles in plurip

NIAID Data Ecosystem90

A genome-wide screen reveals Ints7 deficiency activates endogenous retrovirus MERVL, accompanied by anastasis of embryonic stem cells

胚胎干细胞调控

内源性逆转录病毒激活机制

The murine endogenous retrovirus MERVL is closely associated with the developmental potential of totipotency, manifesting dynamic and reversible activation within a small population of in vitro-cultur

NIAID Data Ecosystem50

H2A.Z.1 mono-ubiquitylation antagonizes BRD2 to maintain poised chromatin in ESCs

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