Transition-metal-free decarboxylative functionalization of α-amino acids
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Decarboxylation of naturally abundant amino acids along with subsequent inter- or intramolecular reaction cascade offers rapid synthesis of a variety of complex and high-value amine derivatives. Previous strategies show a high dependency on transition metals, tedious operations, or harsh conditions. Herein, we reported a novel reaction cascade of α-amino acids decarboxylation and nucleophilic functionalization characterized by transition-metal-free, convenient operation, environmentally benign, and mild conditions.
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Qi, Xiangbing创建时间：
2024-06-20
