Single-cell transcriptome analysis reveals functional changes in tumor-infiltrating B lymphocytes after chemotherapy in esophageal squamous cell carcinoma

Our studies showed that the dynamic change in TIL-Bs functional heterogeneity were involved in the antitumor immune response in ESCC TIME. We used droplet-based single cell RNA sequencing (scRNA-seq) with 23 samples, including 10 tumor samples, 7 normal samples, 5 normal lymph nodes and 1 metastatic lymph node. 16 Samples were re-analyzed from Series GSE197677. The GSE199619_ESCC_NAC.integrated.rds processed data includes the re-analyzed Samples and Sample ESN08.