Next Generation sequencing to evaluate the status on CEACAM5 and CEACAM6 gene in tumor cell lines in order to identify the antigen of the NEO-201 monoclonal antibody (mAb)
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Purpose: The NEO-201 is a mAb that target a tumor-associated form of CEACAM-5 and CEACAM-6 that is not expressed in healthy tissue. NGS was performed to evaluate whether a new CEACAM5 and 6 gene mutation was responsable for this new tumor-associated antigen.
创建时间:
2020-04-15




