Additional file 1 of Efficacy and safety of tart cherry supplementary citrate mixture on gout patients: a prospective, randomized, controlled study

Additional file 1: Table S1. Age related treatment response of the three groups:Participants in the three treatment arms were grouped into > 40 years old or ≤ 40 years old subgroup. Those main outcomes were compared between participants of each subgroup within and between/among these three treatment groups, including ΔUACR, ΔSU, ΔpH, pH ≥ 6.2 at week12 and SU < 360 μmol/L at week 12 in vs in three treatment groups, and no significant difference was observed between subgroups. Table S2. Gout flares in the intent-to-treat set. Fig. S1. DECT urate volumes. Significant differences (p < 0.05) were observed in Sodium bicarbonate, Citrate mixture and TaCCi mixture group between baseline and week 12, while no significant difference was observed between groups. TaCCi Mixture: Tart Cherry supplementary Citrate Mixture. Fig. S2. Serum electrolytes levels during follow up. No significant difference was observed between baseline and week 12 in Sodium bicarbonate, Citrate mixture and TaCCi mixture group. A: Serum potassium,B: serum sodium and C: serum chlorine levels.