RDV and EIDD2801 EC<sub>50</sub> and fold-change in VeroE6-ACE2-TMPRSS2.
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All viruses have a SARS-CoV-2Wu1 backbone with specific point mutations as indicated. Average values and SEM from independently rescued virus stocks, except for rNSP12 E802A. Experiment undertaken at least twice in triplicate by independent operators apart for rNSP6I168T in the presence of EIDD2801 (n = 1) and n = 3 for rSARS-CoV-2, rNSP12E802D, rNSP12E802A and rNSP6I168T. (XLSX)
创建时间:
2021-09-17



