Aripiprazole and olanzapine induce metabolic syndrome and microbiome disorder in rats

Metabolic syndrome is a common problem in schizophrenia, which may be caused by the disease itself or a side effect of treatment drugs. This study explored the relationships of metabolic syndrome caused by the second-generation antipsychotic drugs olanzapine (OLZ) and aripiprazole (ARI) with the gut microbiome.