Supplementary Table 2.xlsx: Concordance of Acquired Mutations between Metastatic Lesions and Liquid Biopsy in Metastatic Colorectal Cancer

<b>Supplementary
Table 2</b>
<b>RAS
index of primary tumors, normal colonic mucosa, and metastatic lesions using
the RASKET kit</b>
Tb
denotes primary tumor tissue obtained before treatment by biopsy, Ts denotes
primary tumor tissues obtained from surgical resection after initial
chemotherapy, and N denotes normal colonic mucosa obtained from surgical
resection after initial chemotherapy.
K2PC,
K3PC, K117PC, K146PC, N2PC, N3PC, N117PC, and N146PC denote the control of
the amplified wild-type allele of KRAS exon 2, KRAS exon 3, KRAS exon 4
(including codon 117), KRAS exon 4 (including codon 146), NRAS exon 2, NRAS
exon 3, NRAS exon 4 (including codon 117), and NRAS exon 4 (including codon
146), respectively.
*G12C
of the S3 sample was considered a false positive, influenced by the strong
positivity of G12R.
†NRAS
codon 117 and 146 indexes of the 2-RL sample were considered “unrecovered”
because the measured values of the N117PC and N146PC beads were lower than
the cut-off value.