Unified cancer and non-cancer transcriptomic data; cancer signatures identified by the TAVNIT software

This dataset contains unified cancer and non-cancer transcriptomic data. Here are data for the entire transcriptome and surfaceome (Supp 1). The data are applicable as input for the TAVNIT software. TAVNIT is a novel tool for cancer subtyping and subsequent extraction of druggable cancer signatures.
Another part of the deposition is the output of TAVNIT executions – cell-surface cancer signatures. The cancer signature represents a record outlining transcription values of some number of genes that are largely sufficient to distinguish cancer samples from non-cancer samples in a given dataset. The deposited signatures are cell-surface ones. Their respective proteins can be potential targets for CAR-T cells. The signatures have been extracted for all cancer samples (Supp 2) and for prostate adenocarcinoma samples (Supp 3).