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Therapeutic efficacy of INX-315, a selective CDK2 inhibitor, in solid tumors [MCF7 and T47D RNAseq]. Therapeutic efficacy of INX-315, a selective CDK2 inhibitor, in solid tumors [MCF7 and T47D RNAseq]

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NIAID Data Ecosystem2026-05-01 收录
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We performed RNA sequencing on T47D and MCF7 cells, both parental and abema- or abema/fulvestrant- resistant, treated with either control vehicle or 300 nM (MCF7) or 100 nM (T47D) INX-315 for 7 days Overall design: Both parental (PAR) and abema-(LYR) or abema/fulvestrant-(LYFR) resistant, treated with either control vehicle or 300 nM (MCF7) or 100 nM (T47D) INX-315 for 7 days. Three replicates per group were collected. 'DMSO' groups denote controls.

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2023-09-13
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