Stromal-compartment methylation associated gene-changes.

DNA methylation of compartmental epithelial and stromal LCM-microdissected human prostate xenografts. Stromal-compartment list of the top ten methylation-associated gene changes that were hypomethylated or hypermethylated. The ratio value corresponds to the average amount of methylation occurring at each site for the individual gene (Ratio values < 1 indicates hypomethylation; Ratio value > 1 indicates hypermethylation). Gestational age of human fetal prostate prior to implantation was 16–21.5 weeks old, and significant difference of q<0.05 was seen between control (C/C) and estradiol benzoate-treated (E/E) samples. Sample size (n) for each group is as follows: control/control (3), and estrogen/estrogen (4), with n representing different individual human fetal prostate samples prior to implantation. Stromal-compartment methylation associated gene-changes.