Two new prenylated indole diketopiperazine alkaloids (PIDAs) penicamides A and B (1 and 2) and three new polyketides penicinones A−C (6−8), along with four known compounds deoxybrevianamide E (3), bre
Examination of the EtOH extract of the leaves of the Malayan Tabernaemontana corymbosa resulted in the isolation of four new (1–4) and two known bisindole alkaloids (5, 6) of the Aspidosperma–Aspidosp
Topoisomerase II (TOP2) inhibitors (TOP2i) are mainstay chemotherapeutic agents that undermine genome integrity by stabilizing TOP2-DNA complexes accompanied by DNA damage formation. Here, we reveal t
ZIP-file containing confocal image stacks from MCF7 (GFP) 3D mono-cultures embedded in alginate capsules and grown in a stirred tank bioreactor. These are the control samples treated with DMSO. Images
Murine B16F10 cells expressing the MICA*001 allele and human lung carcinoma H1703 cells were incubated with a range of doses of IC-PBD2G or MICAB1 PBD2G. After 5-7 days of incubation, the number of li
