Crystal structure of TTBK1 in complex with AMG28

Crystal structure of TTBK1 in complex with AMG28 Descriptor: 1,2-ETHANEDIOL, 4-(2-amino-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-11-yl)-2-methylbut-3-yn-2-ol, PHOSPHATE ION, ... Authors: Chaikuad, A, Axtman, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2022-04-06 Release date: 2023-04-19 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis. Sci Rep, 13, 2023