Identification of the Side Products That Diminish the Yields of the Monoamidated Product in Metal-Catalyzed C–H Amidation of 2‑Phenylpyridine with Arylisocyanates
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The Ru(II)-catalyzed amidation of 2-arylpyridines with aryl isocyanates via C–H bond activation is less efficient than described previously, due to the formation of a series of side products, which were readily identified using direct infusion electrospray mass spectrometry and high-performance liquid chromatography–mass spectrometry.
创建时间:
2020-01-23



