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A quantitative model of transcription regulation reveals the role of non-conserved enhancers

ChEBI2010-05-12 更新2026-07-21 收录

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-17067 数据链接链接失效反馈

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A quantitative model of transcription regulation reveals the role of non-conserved enhancers

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创建时间：

2010-05-12

基因治疗研究

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X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disorder caused by mutations in the ABCD1 gene that encodes the peroxisomal ATP-binding cassette (ABC) transporter subfamily D member 1 protein (

NIAID Data Ecosystem30

Structure of transcription regulator CcpA in its DNA-free state

蛋白质结构解析

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Structure of transcription regulator CcpA in its DNA-free state

NIAID Data Ecosystem20

A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals distinct transcriptional properties and context-dependent binding and regulation of target genes (ChIP-Seq)

白血病融合蛋白

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The ETO-family transcriptional corepressors, including ETO, ETO2 and MTGR1, are all involved in leukemia-causing chromosomal translocations. In every case, an ETO-family corepressor acquires a DNA-bin

NIAID Data Ecosystem10

Co-regulated gene expression downstream of a single transcription factor controls the acquisition of corticospinal motor neuron identity

神经元亚型

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The neocortex contains an unparalleled diversity of neuronal subtypes responsible for complex behavior. Each cortical neuron has distinct traits, which are developmentally acquired under the control o

NIAID Data Ecosystem20

BHLHE40 is key hypoxia-induced transcriptional repressor in beta cells. BHLHE40 is key hypoxia-induced transcriptional repressor in beta cells

细胞缺氧反应

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To assess the impact of hypoxia on global gene expression of beta cells, we performed bulk RNA-seq on mouse islets, human islets and MIN6 cells. Bhlhe40 was transcriptional repressor which was highly

NIAID Data Ecosystem20

A quantitative model of transcription regulation reveals the role of non-conserved enhancers

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