Myocardial Applied Genomics Network (MAGNet) Study

The MAGNet repository includes non-failing samples from organ donors with no history of heart failure and failing samples from explanted hearts of donors receiving a heart transplant. The study protocol was approved by the Institutional Review Board at the University of Pennsylvania, and all patients provided written informed consent to participate.]]> The samples used for the current analyses are a combination of normal heart transplant donors and samples from donors with dilated cardiomyopathy, hypertrophic cardiomyopathy, or ischemic cardiomyopathy.]]> MAGNet is a collaborative group of investigators who use genomic approaches to understand human myocardial disease. Current projects include human myocardial expression, quantitative trait mapping, and systems genetics.]]>