Human cathepsin-C in complex with cyclopropyl peptidyl nitrile inhibitor 1
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6ic6
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Human cathepsin-C in complex with cyclopropyl peptidyl nitrile inhibitor 1 Descriptor: (2~{S})-~{N}-[(1~{R},2~{R})-1-(aminomethyl)-2-[4-[4-(trifluoromethyl)phenyl]phenyl]cyclopropyl]-2-azanyl-butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... Authors: Hakansson, M, Logan, D.T, Korkmaz, B, Lesner, A, Wysocka, M, Gieldon, A, Gauthier, F, Jenne, D, Lauritzen, C, Pedersen, J. Deposit date: 2018-12-02 Release date: 2019-04-24 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.898 Å) Cite: Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C. Biochem. Pharmacol., 164, 2019
创建时间:
2018-12-02



