Results of Cochran's Q test for heterogeneity on single-trait IVW MR results for the effect of a lipid trait on ER+ versus ER− BC.

Trait: lipid trait used as the exposure; ERposBeta: MR effect estimate for ER+ BCs; ERnegBeta: MR effect estimate for ER− BCs; ERposSE: standard error of MR effect estimate for ER+ BCs; ERnegSE: standard error of MR effect estimate for ER− BCs; Q: Cochran’s Q test statistic; P: P-value of Cochran’s Q test. BC, breast cancer; ER, estrogen receptor; HDL, high-density lipoprotein; IVW, inverse-variance weighted; LDL, low-density lipoprotein; MR, Mendelian randomization; TC, total cholesterol; TG, triglyceride. (XLSX)