DNA methylation profiling upon treatment with NTX-301 or decitabine in AML cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE187291
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A novel hypomethylating agent NTX-301 is a promising therapeutic agent for AML patients. To examine its mechanisms of action, we produced methylome data upon treatment with NTX-301 or decitabine (DAC) in MV4-11 cell line. Leukimia cells (MV4-11 and HL-60) were cultured using the RPMI1640 medium. Cells were plated on 10cm dishes at the day before drug treatment, and DMSO, NTX-301 (60nM), and DAC (60nM) were treated during 48h. After extracting genomic DNA and assessing DNA QC,
创建时间：
2023-04-04
