Transcriptome from mouse Ts65Dn adult hippocampi and entorhinal cortices
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https://www.ncbi.nlm.nih.gov/sra/SRP397613
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We have created the Ts66Yah a new model for Down syndrome or T21, derived from the Ts65Dn. Ts66Yah does not contain a set of genes present in 3 copies that are not linked to T21. On this model (Ts66), we performed an RNA seq analysis on 2 structures (hippocampus and entorhinal cortex, ref: S18276) and we have done the same experiment on the Ts65Dn line to compare the 2 models. For this we sampled the hippocampus (hippo) and the entorhinal cortex (EntCortex) from 6 wild-type control male littermate animals and 6 males trisomic individual (Ts66 or Ts65). Overall design: 12 individuals, 6 control and 6 Ts, 2 brain regions Hippocampus and Entorhinal cortex
创建时间：
2023-02-28
