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Additional file 1 of A compendium of synthetic lethal gene pairs defined by extensive combinatorial pan-cancer CRISPR screening

NIAID Data Ecosystem2026-05-10 收录

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癌症基因功能

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https://figshare.com/articles/dataset/Additional_file_1_of_A_compendium_of_synthetic_lethal_gene_pairs_defined_by_extensive_combinatorial_pan-cancer_CRISPR_screening/30162350 数据链接链接失效反馈

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Additional file1

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创建时间：

2025-09-18

癌症基因功能

基因表达谱分析

Affymetrix Hu133 GeneCHIP Microarray data for Control and c-MYC knock-down (KD) human cancer cell lines. Data related to article 'Novel c-MYC target genes mediate differential effects on cell prolife

NIAID Data Ecosystem120

The whole transcriptome expression profiling comparison between the CtBP1 knockdown, CtBP2 knockdown and scramble control in ovarian cancer SKOV3 cells

癌症基因功能

转录组分析

To discover the core gene expression features of CtBP1, CtBP2 differently regulated in ovarian cancer SKOV3 cells. The compared the whole transcript expression profiling between CtBP1 knockdown, CtBP2

NIAID Data Ecosystem40

Additional file 3 of Large-scale copy number alterations are enriched for synthetic viability in BRCA1/BRCA2 tumors

癌症基因治疗

合成致死筛选

Additional file 3: Table S2. Guide-RNA target sequences for the validated synthetic viable genes.

NIAID Data Ecosystem20

Conditional expression of oncogenic KrasG12D and HrasG12D alleles in mouse keratinocytes reveals a dose dependent requirement for tumor formation.. Conditional expression of oncogenic KrasG12D and HrasG12D alleles in mouse keratinocytes reveals a dose dependent requirement for tumor formation.

皮肤癌模型

癌症基因功能

The discovery that activation of the Hras gene was the driver mutation for tumor development in mouse skin treated with 7,12-dimethylbenz(a)anthracene illuminated the link between environmental and mo

NIAID Data Ecosystem40

Candidate genes and pathways involved in TTK-induced biological functions in ovarian carcinoma. Candidate genes and pathways involved in TTK-induced biological functions in ovarian carcinoma

癌症基因功能

TTK基因机制

TTK has been shown to participate in the tumorigenesis of several cancer types but little is known about the function and molecular signalling in ovarian cancer cells. In this study we aim to identify

NIAID Data Ecosystem30

Additional file 1 of A compendium of synthetic lethal gene pairs defined by extensive combinatorial pan-cancer CRISPR screening

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