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资源简介：
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
应用场景：
创建时间：
2013-12-26
相关数据集
Next-Generation Sequencing Facilitates Quantitative Analysis of WT, Ring1a-/-, Ring1b-/-, Ring1a/b-/-, Pcgf1/3/5/6-/- and Pcgf1/2/3/4/5/6-/- Embryonic Stem Cells Transcriptomes
Polycomb repressive complexes (PRC) are epigenetic transcriptional repressors by establishing facultative heterochromatin repressive domains and play an essential role in numerous developmental proces
NIAID Data Ecosystem80
A Cbx8-containing Polycomb complex facilitates gene activation during ES cell differentiation [ChIP-Seq]
Polycomb proteins play an essential role in maintaining the repression of developmental genes in self-renewing embryonic stem cells. The exact mechanism allowing the derepression of polycomb target ge
NIAID Data Ecosystem70
Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of lineage genes [ChIP-Seq]
Polycomb group (PcG) proteins play important roles in repressing lineage-specific genes and maintaining the undifferentiated state of mouse embryonic stem cells (mESCs). However, the mechanisms by whi
NIAID Data Ecosystem50
Dynamic antagonism between key repressive pathways maintains the placental epigenome (ChIP-seq). Dynamic antagonism between key repressive pathways maintains the placental epigenome (ChIP-seq)
DNA and Histone-3 Lysine 27 methylation typically function as repressive modifications and operate within distinct genomic compartments. In mammals, the majority of the genome is kept in a DNA methyla
NIAID Data Ecosystem70
Functional Landscape of PCGF Proteins Reveals Both RING1A/B Dependent and Independent Specific Activities. Functional Landscape of PCGF Proteins Reveals Both RING1A/B Dependent and Independent Specific Activities
Polycomb repressive complexes 1 and 2 (PRC1 and PCR2) control cell identity by establishing facultative heterochromatin repressive domains at common sets of target genes. PRC1, which deposits H2Aub1 t
NIAID Data Ecosystem50
